Select Page

Integration: Drug Interactions

The most comprehensive drug-drug, drug-herbal, drug-food, and drug-lifestyle interactions checker available on the market.

The PEPID Knowledgebase contains the most robust, actionable drug interactions and alerts databases available on the market. Approaching nearly 5 million interactions, the PKB DI ensures safer prescribing and administration of medications from around the world. 

Drug Interactions Database Contents

Cross-check entire medication lists for drug interactions with the largest drug and substance database on the market

  • Intuitive user interface eliminates steps to check for interactions
  • Checks entire medication lists simultaneously
  • Checks for interactions against:
    1. Prescription and OTC drugs (over 100,000 drug products)
    2. 900+ nutraceuticals, including herbal medicines
    3. Toxic and controlled substances
    4. Individual lifestyle factors
  • Immediately view interaction summaries for entire medication list

Add treatments, filter results, prescribe safely and accurately

  • Interaction summaries jump to complete interaction monographs that include:
    1. Mechanism of Interaction
    2. Effect
    3. Level of Concern
    4. Action, including alternative drugs
    5. References
  • Presented in prescriptive, immediately actionable bullet points for busy clinicians and students
  • Jump directly to relevant drug and clinical content
  • Filter interactions by severity or drug
  • Immediate access to relevant, prepopulated adult and pediatric dosing information and calculators

Industry Leading Drug Information

Unbiased Drug Content

Continuously Updated, Rigorously Reviewed

Works Within Any System

Budget Friendly

Delivery Options


Designed for ease of implementation, PEPID supports InfoButton implementations that make integrating industry-leading CDS as simple and painless as possible.

PKB Extensions

Built off a platform designed for rapid integrations, PKB Extensions leverages a complete back-end system that accepts any nomenclature and returns immediately displayable CDS content and tools.

API / Web Services

Get total control over your drug and clinical reference data, with robust API delivery that allows you to design and display alerts and information at the most relevant points in the user workflow.

Flat File / Custom Export Structure

Localized databases with import scripts to drop any information into any existing system. Both US + Canadian and International Agnostic versions available. Custom export structures and designs available to meet any system requirements.

A leader and trusted name in mobile and integrated point-of-care solutions for over 25 years, PEPID’ s profession-tailored point-of-care information resources and clinical modules support thousands of healthcare practitioners and institutions across 159 countries.

Our Drug Interactions Checker is backed by the PEPID Knowledgebase (PKB), which houses the largest drug database on the market. It is continuously reviewed and updated by highly qualified clinicians and in close partnership with the American Society of Health System Pharmacists (ASHP).